Can't reach the ec2 instance

I'm sorry you're having trouble connecting to your instance.

The EC2 User Guide provides a troubleshooting section with troubleshooting information specifically for the "connection timed out" error at this link: https://docs.aws.amazon.com/AWSEC2/latest/UserGuide/TroubleshootingInstancesConnecting.html#TroubleshootingInstancesConnectionTimeout

I hope this helps.

Kind regards,
Marilyn
AWS Documentation

If the security groups/NACLs are fine, check if the route tables allow communication from the internet to the subnet in which the Ec2 is located. Also see if you have a IGW