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Hello,
Please try this solution.
The best AWS region for cost-efficient EC2 Spot Instances use the AWS Spot Instance Advisor to identify regions with low interruption rates and high savings. Then use the AWS CLI to check the current Spot prices for your required instance types (EX. c5.9xlarge, c5.18xlarge) and compare prices across regions. Next set up an AWS Batch compute environment via the AWS Management Console, selecting "Managed" and "SPOT" as the compute resource type and specifying the maximum vCPUs and desired instance types. Lastly, consider data transfer costs by using the AWS Pricing Calculator to estimate data egress fees for your selected regions. you can quickly and easily determine the most cost-effective region for your Spot Instance workload.
if you need more information, please go through the AWS Document Link.
https://spot.io/resources/aws-ec2-pricing/the-ultimate-guide/
Please follow below documentation,
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