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Hello.
I also encountered a 403 error with Claude fable-5 on my personal AWS account, just like you.
Usage restrictions may be in place for AWS accounts with limited usage history or those that are not enterprise-level accounts.
It is possible that this situation will persist until demand stabilizes.
https://aws.amazon.com/jp/blogs/aws/anthropic-claude-fable-5-on-aws-mythos-class-capabilities-with-built-in-safeguards-now-available/?trk=d8ec3b19-0f37-4f8c-8c12-189f913e205c&sc_channel=el
Model access: Claude Fable 5 access is gradually expanding for all AWS accounts. If your account doesn’t have access yet, it will be enabled soon depending on your Bedrock usage. If you want to get access to this model quickly, contact your usual AWS Support.
The availability API and actual invocation check two different things, which is what makes this confusing. get-foundation-model-availability tells you the model exists and your account has it enabled in the console, but InvokeModel still needs your IAM role to explicitly allow the resource ARN being called.
For the newer Claude models (Opus 4/5, Sonnet 5) Bedrock requires you to invoke them through a cross-region inference profile, not the bare foundation-model ARN. The resource in your IAM policy needs to include both the inference-profile ARN and the foundation-model ARN in the destination regions, not just one or the other. If you have an SCP in AWS Organizations that restricts regions, that can silently block the cross-region routing too even when model access looks granted.
Two quick things worth checking: does your IAM role's policy allow bedrock:InvokeModel on arn:aws:bedrock:REGION:ACCOUNT_ID:inference-profile/* alongside the foundation-model/* ARN? And is there an SCP denying actions in any of the regions Bedrock would route to under the inference profile?
There's a Knowledge Center article specifically on the AccessDeniedException with cross-region inference profiles in Organizations accounts at repost.aws/knowledge-center/bedrock-access-denied-exception that has example policy fixes. I'm happy to take a look at your policy setup and point you to the exact fix if you share what model ID string you're passing in the API call.
answered 2 months ago
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