Can RDS Proxy be used with Blue/Green deploy?

Unfortunately, Amazon RDS Blue/Green Deployments still do not support Amazon RDS Proxy. This limitation remains in place and has not changed since it was initially introduced. Blue/Green Deployments are designed to provide safer, simpler, and faster database changes with minimal downtime, but they have specific limitations, one of which is the lack of support for RDS Proxy.

This limitation applies across different database engines supported by Amazon RDS, including PostgreSQL and MariaDB. It's important to note that along with RDS Proxy, Blue/Green Deployments also do not support other features such as cross-Region read replicas and cascaded read replicas.

When planning database updates or changes using Blue/Green Deployments, you'll need to consider alternative approaches if you're currently using or planning to use RDS Proxy. It's always a good idea to review the most current AWS documentation or consult with AWS support for the latest information on feature compatibility and best practices for your specific use case.
Sources
Amazon RDS for PostgreSQL FAQs – Amazon Web Services (AWS)
Amazon RDS for MariaDB FAQs – Amazon Web Services (AWS)
Limitations and considerations for Amazon RDS blue/green deployments - Amazon Relational Database Service